| Date | Location | Result | |
| 2/20/16 | Branch Rickey Arena; Delaware, Ohio, USA | Ohio Wesleyan 81, DePauw University 57 | Box score |
| 2/17/16 | Greencastle, Ind. | DePauw University 114, Wabash 110 (3OT) | Box score |
| 2/13/16 | Greencastle, Ind. | Kenyon College 81, DePauw University 79 | Box score |
| 2/10/16 | Springfield, OH (Pam Evans Smith Arena) | Wittenberg 85, DePauw University 53 | Box score |
| 2/6/16 | Greencastle, Ind. | Hiram College 72, DePauw University 65 | Box score |
| 2/5/16 | Greencastle, Ind. | Allegheny 59, DePauw University 54 | Box score |
| 1/30/16 | Oberlin, Ohio - Philips Gym | DePauw University 64, Oberlin College 53 | Box score |
| 1/27/16 | Livingston Gymnasium in Granville, Ohio | Denison 81, DePauw University 60 | Box score |
| 1/23/16 | Greencastle, Ind. | Wooster 73, DePauw University 56 | Box score |
| 1/20/16 | Crawfordsville, IN | Wabash 80, DePauw University 75 | Box score |
| 1/16/16 | Greencastle, Ind. | Ohio Wesleyan 74, DePauw University 67 | Box score |
| 1/13/16 | Greencastle, Ind. | Wittenberg 65, DePauw University 42 | Box score |
| 1/9/16 | Gambier, OH (Tomsich Arena) | Kenyon College 82, DePauw University 75 | Box score |
| 1/4/16 | Hiram, Ohio - Price Gym | Hiram College 91, DePauw University 60 | Box score |
| 1/3/16 | Meadville, Pa. | DePauw University 67, Allegheny 64 | Box score |
| 12/30/15 | Tampa Prep; Tampa, Fla. | DePauw University 81, Buena Vista 79 | Box score |
| 12/29/15 | Tampa Prep; Tampa, Fla. | DePauw University 82, Coast Guard 71 | Box score |
| 12/12/15 | Greencastle, Ind. | DePauw University 75, Oberlin College 66 | Box score |
| 12/5/15 | Wooster, Ohio | Wooster 85, DePauw University 56 | Box score |
| 12/2/15 | Greencastle, Ind. | Denison 80, DePauw University 67 | Box score |
| 11/29/15 | Terre Haute, Ind. - Hulbert Arena | Rose-Hulman 76, DePauw University 67 | Box score |
| 11/24/15 | Richmond, Ind. | DePauw University 80, Earlham 74 | Box score |
| 11/21/15 | St. Louis, Mo. (WU Field House) | Pomona-Pitzer 77, DePauw University 74 | Box score |
| 11/20/15 | St. Louis, Mo. (WU Field House) | Johns Hopkins 82, DePauw University 74 | Box score |
| 11/17/15 | Greencastle, Ind. | DePauw University 84, Franklin College 79 | Box score |